TheCamelHerder | 11 points
Regular dosing of ivermectin for prophylactic purposes - was this done in the past?Prior to the coronavirus, was ivermectin recommended for regular use (once a week or once a month, for example) or is this a novel recommendation? In other words, do we know the safety or dangers associated with repeated ivermectin use, as opposed to a one-time treatment?
[-] [deleted] | 3 points
There was this study (which got me suspended on twitter 😬)
They looked at safety of single (up to 10 times FDA approved) & 3 dose schedule. Not exactly what you were asking tho.
https://accp1.onlinelibrary.wiley.com/doi/abs/10.1177/009127002237994
[-] Ivermectin4all | 2 points
No, according to Dr. Kory, we have never done longterm regular prophylaxis prior to covid. Pierre answers this in one of his weekly updates. If I find the link I will share.
Edit: https://youtu.be/nPjH4NfHjR4?t=1319
My wife and I are 73 years old and have been taking IVM prophetically for 8 months (weekly). We know there is no study concerning the long-term effects of IVM at such an interval, but we are also HIGHLY confident that it is completely protecting us from Covid-19. In fact my spouse has been in direct contact with two persons who within a few days after her contact tested Covid positive. One of those persons died, the other asked her about IVM and we gave her some....she never got any sicker than she was the day she started the IVM and completely recovered within a few days. She and I both tested negative. We will continue to take our weekly dose (.2mg/kg) at least until such time as the EXPERIMENTAL Covid-19 vaccine becomes FULLY approved by the FDA, not just used under an "Emergency Use Authorization".
[-] BernieTheDachshund | 2 points
It helped my grandma, mom, and sister. So nice to see others it has helped!
[-] stereomatch | 1 points
It helped my grandma, mom, and sister. So nice to see others it has helped!
Would you care to post a detailed with timeline post (esp. noting day 1 of first symptoms and so on) - and flair it as a case study?
It may be instructive for others.
[-] BernieTheDachshund | 2 points
People have to take it repeatedly for scabies, so it's not always a one time treatment. It's one of the safest meds on the planet, does not have a long half-life so it won't hurt to take it on a schedule. Some people take it for rosacea too, there's some mites that live on our faces and they are thought to contribute to it.
[-] only_dreaming_09 | 4 points
First time my Rosacea has ever cleared up. Now taking every two weeks...
[-] BernieTheDachshund | 2 points
That's awesome! I've read tea tree oil products can help too.
[-] RogerKnights | 2 points
But those are topical uses, not internal. I’ve read that ivermectin is approved in the U.S. for internal treatment of intestinal worms. Can anyone confirm?
[-] beepmonster | 6 points | Apr 15 2021 20:43:03
Full article: Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection
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[-] stereomatch | 4 points | Apr 16 2021 06:29:20
Full article: Continuous high-dose ivermectin appears to be safe in patients with acute myelogenous leukemia and could inform clinical repurposing for COVID-19 infection https://www.tandfonline.com/doi/full/10.1080/10428194.2020.1786559
This is a very interesting paper - which showed ivermectin benefit for leukemia - although not enough that it could save the severely ill patients who eventually died (but evidently lived longer than they were expected to on average).
The authors however do point out - (thanks to the sacrifice of these patients) - we have the data to indicate that very high doses of ivermectin - they used 1mg/kg (compared to the typical 0.2mg/kg) for 14 days to 6 months continuously (!) (compared to the typical 1 day to 5 days with refresher doses usually used for covid19).
That is not to say that covid19 patients need such high doses - but it does establish visibility into the safety profile for ivermectin should high doses be needed.
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