Currently taking Ivermectin for parasites. How long between last dose should I do before I get the Covid vaccine? And AFTER taking the vaccine, when can I take it again if needed?

[-] Swineservant | 5 points | Mar 28 2021 03:50:30

Dr. Been's take on how that works: "Will Ivermectin Block a Vaccine?" https://www.youtube.com/watch?v=aYo6Y71WwkU

TL;DW: It shouldn't interact/affect vaccines.

[-] machinelearny | 2 points | Mar 28 2021 17:59:49

While Dr. Carvallo said you should probably stop 10 days before and start again 10 days after.

Personally I would probably take it again sooner after getting vaccinated - like 5 days after? Since I just have a feeling something is up with these spikes of covid seen everywhere just after mass vaccination started, I'd take even more precautions than before during that 20 day period after vaccination, just to be safe :) But that's just based on speculation.

[-] Mex_Rover52 | 3 points | Mar 29 2021 14:00:15

Do you have a link for this info from Dr. Carvallo? I'm due for my biweekly IVM prophy dose today, but read that the Cansino one-shot vaccine campaign will begin in my Mexican town later this week for age 60+ folks like me. Cansino is human Adenovirus based, like J&J, and I'm not sure that Dr. Mobeen's analysis is applicable to non-mRNA vaccines. Thanks!

(BTW, Ivermetin in a box of four 6 mg tablets is readily available over the counter locally. Price per box varies from 99 to 183 Mexican pesos, or about 5 to 9 USD.)

[-] machinelearny | 1 points | Apr 02 2021 23:33:43

based

Sorry, I don't remember the exact video. It was a video where I think MoBeen was interviewing like 5 doctors, Dr. Kory, Carvallo, Tess, some other ppl.

Anyway, I wasn't really aware, but it seems the adenovirus version is really just another packaging of mRNA. The adenovirus is used to get the mRNA inside your cells instead of the lipid nanoblob-thingy. Once the adenovirus enters your cells, the same process happens, your cells start producing spike protein. So the same principles wrt ivermectin use would probably apply. Unless the ivermectin will hinder the cell entry of the adenovirus more than it would the lipid nanathingies, in which case it might make the vaccine less effective. Anyway, that's just my clueless interpretation :)

Probably best to stop use about a week to 10 days before and give it a few days to generate an immune response and then wack it with some ivermectin before it starts causing havoc :)

[-] Mex_Rover52 | 1 points | Apr 03 2021 03:12:35

I have the same problem finding material I've seen in videos because the content is not indexed. In another Dr. Mobeen video (which now I can't find), he said he saw no mechanism of action that would cause IVM to interfere with vaccines, but he also gave Dr. Carvallo's opinion to stop 14 days before and resume 14 days after. I ended up stopping 17 days before receiving Cansino yesterday, and will resume IVM 14 days later. However, I'm stocked and prepared to take daily doses of IVM if Covid symptoms appear during that interval.

To correct one point above, adenovirus vaccines use DNA, not mRNA. This allows for incorporating much longer sequences, like the encoding for the entire spike protein, where as the smaller, more fragile mRNA typically include only a subset of proteins from the spike (17 for Pfizer, 10 for Moderna). DNA is more robust than mRNA, which is why adenovirus vaccines do not require the super-cooling of mRNA vaccines and are easier to transport and store. And using the entire spike provides more targets to train antibodies, potentially making DNA vaccines less vulnerable to variant mutations that might eliminate part of the protein subset that mRNA vaccines encoded for.

[-] machinelearny | 1 points | Apr 03 2021 04:06:15

Ok, yeah, I was mistaken before. It's DNA encapsulated within the adenovirus protein, not mRNA as I thought, and then the DNA must enter the nucleus where it is read and the nucleus then makes the spike protein mRNA and then the mRNA leaves the nucleus and the cells make the spike proteins (or whatever proteins are encoded in the mRNA). So there's a few more steps. Did I get it right this time?

I didn't know that Pfizer and Moderna had different amounts of proteins, that's interesting, so they should have quite different characteristics in terms of mutations.

[-] machinelearny | 1 points | Apr 03 2021 04:07:42

Cansino

Is the Cansino vaccine inhaled?

[-] Mex_Rover52 | 1 points | Apr 03 2021 04:35:34

No. It's a conventional injection in the arm deltoid muscle. My wife had slight injection site soreness last evening. I had none.