I-MASK+ Prophylaxis & Early Outpatient Treatment Protocol For Covid-19 (PDF) (US 2020-11-09) Prophylaxis regimen changed, more ivermectin in first 10 weeks
lvermectin Prophylaxis for high risk individuals
0.2 mg/kg — one dose on day 1 and day 3, then take one dose weekly for 10 weeks, followed by one dose every 2 weeks*
Post COVID-19 exposure prophylaxis**
0.2 mg/kg — one dose on day 1 and day 3
Vitamin D3 1,000–3,000 IU/day
Vitamin C 1,000mg twice a day
Quercetin 250mg/day
Zinc 50mg/day
Melatonin 6mg before bedtime (causes drowsiness)
* ≈ 0.09 mg/lb per dose (take on an empty stomach with water). Example for a person of 60kg (body weight): 60kg × 0.2mg = 12mg — please see conversion table (kglbs) on page 2 to calculate the appropriate ivermectin dose.
** This dosing may be updated as further scientific studies emerge.
*** To use if a household member is COVID-19 positive, or you have prolonged exposure to a COVID-19 positive patient without wearing a mask
I think the "take on an empty stomach" is the standard dosing when taken for parasites. It has been mentioned on here about taking it with a "fatty" meal. I'm not sure what a fatty meal is, but it would slow down digestion and perhaps absorption--so presumably more IVM would be absorbed.
Just to clarify--Are you saying 2.5 times as much IVM gets into the blood stream when taken right after a fatty meal?
IF so I wonder why they still say "on an empty stomach"?
I'm not sure that "right after" is correct. Dr. Aguirre recommends taking ivermectin 2 hours after eating. Presumably that allows time for the fatty meal to "take effect".
why they still say "on an empty stomach"?
I assume that that's reflexive caution, which IMO is unwarranted. I imagine that they are thinking "If the fatty meal increases the blood level of IVM, that's dangerous" -- except it's not. Ivermectin is ridiculously safe.
An Italy trial is dosing at 1200mcg/kg for 5 consecutive days -- which will produce MUCH higher blood levels than augmenting a 200mcg/kg dose by 2.5 times. Several trials are dosing at 600mcg/kg.
Is that a satisfactory answer? Not being snarky, I just want to make sure that I've spoken to your concerns.
[-] TrumpLyftAlles | 3 points | Dec 11 2020 23:01:38
PROPHYLAXIS PROTOCOL
lvermectin Prophylaxis for high risk individuals
0.2 mg/kg — one dose on day 1 and day 3, then take one dose weekly for 10 weeks, followed by one dose every 2 weeks*
Post COVID-19 exposure prophylaxis**
0.2 mg/kg — one dose on day 1 and day 3
Vitamin D3 1,000–3,000 IU/day
Vitamin C 1,000mg twice a day
Quercetin 250mg/day
Zinc 50mg/day
Melatonin 6mg before bedtime (causes drowsiness)
* ≈ 0.09 mg/lb per dose (take on an empty stomach with water). Example for a person of 60kg (body weight): 60kg × 0.2mg = 12mg — please see conversion table (kglbs) on page 2 to calculate the appropriate ivermectin dose.
** This dosing may be updated as further scientific studies emerge.
*** To use if a household member is COVID-19 positive, or you have prolonged exposure to a COVID-19 positive patient without wearing a mask
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[-] rondi7 | 5 points | Dec 12 2020 00:04:11
I think the "take on an empty stomach" is the standard dosing when taken for parasites. It has been mentioned on here about taking it with a "fatty" meal. I'm not sure what a fatty meal is, but it would slow down digestion and perhaps absorption--so presumably more IVM would be absorbed.
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[-] TrumpLyftAlles | 3 points | Dec 12 2020 00:10:55
Either 2.5 or 2.6 (I've seen both numbers, the difference is immaterial) times more ivermectin in the blood stream, which is what you want. IMO.
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[-] rondi7 | 2 points | Dec 12 2020 17:42:31
Just to clarify--Are you saying 2.5 times as much IVM gets into the blood stream when taken right after a fatty meal?
IF so I wonder why they still say "on an empty stomach"?
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[-] TrumpLyftAlles | 1 points | Dec 12 2020 18:13:04
I'm not sure that "right after" is correct. Dr. Aguirre recommends taking ivermectin 2 hours after eating. Presumably that allows time for the fatty meal to "take effect".
why they still say "on an empty stomach"?
I assume that that's reflexive caution, which IMO is unwarranted. I imagine that they are thinking "If the fatty meal increases the blood level of IVM, that's dangerous" -- except it's not. Ivermectin is ridiculously safe.
An Italy trial is dosing at 1200mcg/kg for 5 consecutive days -- which will produce MUCH higher blood levels than augmenting a 200mcg/kg dose by 2.5 times. Several trials are dosing at 600mcg/kg.
Is that a satisfactory answer? Not being snarky, I just want to make sure that I've spoken to your concerns.
permalink