alishock | 6 points | Nov 04 2020 20:36:58

In theory, would Ivermectin still work against the new Denmark mutation of COVID-19?

Ok, I'm just trying to find peace through this sub since Ivermectin has been my biggest hope in case I get Covid-19, but with the news from today, I'm worried out of my mind all over again, though maybe it's a momentary over exaggeration of course but I wanted to see the cards that might be played in the worst case scenario.

Obviously it's still WAY too early to know what this might imply, if it can actually get out of Denmark at all or what its different characteristics are, but I just wanted to ask whoever might have an idea on coronaviruses and ivermectin interaction in general here after all the research that has been done:

Does Ivermectin also work on other Coronaviruses that are not Covid-19? As in, has some research been done against SARS and such that might also prove that ivermectin is also effective enough against those and might also be to this new one?

Some pages theorize that the immunity against COVID-19 antibodies that the new batch has might be because mutations on the outer spikes of the virus rather than the interior, but I digress.

Is there still hope against the new mutation based off the previous ivermectin research in case it gets out of Denmark?

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[-] Z3rul | 4 points | Nov 04 2020 21:21:43

ivermectin doesn't attack the virus, in simple words it helps your body to stop virus replication. so yes it will probably work against new mutations.

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[-] SwiftJustice88 | 4 points | Nov 04 2020 22:07:39

It should! Throw some black seed oil into your cabinet too for peace of mind, the recent study that came out looks promising. https://www.medrxiv.org/content/10.1101/2020.10.30.20217364v1

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[-] alishock | 1 points | Nov 30 2020 19:58:42

I'm sorry for the late, late reply, haha

The study just mentions Black Seeds, right? As in, they didn't give them the oil straight-up, just the actual seeds?

I ask since my country doesn't really have oil to sell :c The few ones that are available are WAY too expensive due to the importation costs, and aside from that I could only just find the seeds as condiment.

Do you know how I could clean and "cook" the seeds properly to get the most out of the oil and nutrients and such? Or do you know any place that explains it to a t? I've never eaten (or prepared for that matter) these kind of seeds/suppliments and I wanna start not just for the COVID protection, but for the countless benefits I've found out about it very recently.

Sorry to bother! I just didn't know where to look first for myself :c

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[-] rraak | 3 points | Nov 04 2020 21:35:37

I don't see any reason why it wouldn't. It's been shown in some studies to be useful for flu prophylaxis e.g., https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048202/

This means it's probably useful for a lot of different viruses including cold and flu.

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[-] Haitchpeasauce | 3 points | Nov 04 2020 22:51:25

Ivermectin's action are broadly antiviral because they target downstream mechanisms within the cell. It won't protect against the entry of virus into the cells, but it will inhibit the replication of the virus and inhibit the immune dysregulation the virus can cause - the body will be able to respond correctly and swiftly to the virus.

With regards to the mutation of SARS-CoV-2 in minks, it's not known yet whether a mutation that goes on to infect humans again would produce a worse disease or a weaker one. It's not known whether people with SARS-CoV-2 immunity will mount a successful response if challenged by the mink mutation of the virus; if their antibodies and T cells will recognise the virus. The spike protein would have to be similar enough to bind with human ACE2 again, but that's just me speculating.

Someone with a microbiology/virology degree will have a proper opinion.

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[-] Ok-Film-9049 | 1 points | Nov 04 2020 20:53:37

I going with yes. It works with the mice and a similar virus

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