JezSan | 16 points | Oct 29 2020 23:12:57

Latest MATH+ Protocol from Paul Marik & EVMS - highly recommends Ivermectin

https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdf

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[-] SwiftJustice88 | 4 points | Oct 29 2020 23:46:09

Wow, that was a rapid turn of events from optional to highly recommended. I’m not too familiar with Dr. Marik outside of this protocol but he’s a fairly big name in the medical community correct? I am so anxious to see more studies come through with their findings!

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[-] TrumpLyftAlles | 4 points | Oct 29 2020 23:50:54

The newest version is dated 2020-10-29.

Ivermectin is no longer optional!

Among HCQ, Remdesivir, and 6 other drugs, only ivermectin is effective in all phases.

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[-] thaw4188 | 4 points | Oct 30 2020 01:15:34

I just don't get the single day doses.

They've obviously concluded it does something and is safe, yet they somehow believe for even severe cases that just two days is fine.

I needed days and days as a severe case, even multiple treatments, with only two days I would have died.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 01:17:30

You really went through hell. I still wince, remembering.

But you came to ivermectin late, right? Week 5 or something?

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[-] thaw4188 | 3 points | Oct 30 2020 01:25:02

yeah very late, I was also on steroids which knocked out any remainder of my immune system but after so many weeks my immune was clearly not going to win anyway

still two days seems like they think it's way more powerful than it actually is

it's not powerful, it's just a "broad spectrum" anti-viral with weak targeting that happens to work on covid (fortunately)

they also believe in it as a preventative which I strongly disagree with, there is no way they have proof because there's no such study unless you know of one

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[-] TrumpLyftAlles | 2 points | Oct 30 2020 01:29:38

it's not powerful, it's just a "broad spectrum" anti-viral with weak targeting that happens to work on covid (fortunately)

Targetting imp a/b1 seems not-weak to me?! With covid-19, there are other happy bindings, if you believe molecular studies.

they also believe in it as a preventative which I strongly disagree with, there is no way they have proof because there's no such study unless you know of one

Dr Aguirre's study (very small), Egypt, Argentina. I take prophylaxis as proven. The first hand experience of hundreds of health workers in Latin America, India and Bangladesh (barely documented).

Why the skepticism?

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[-] thaw4188 | 3 points | Oct 30 2020 01:35:52

the once a week 12mg as prophylaxis just seems completely implausible unless you get really lucky with timing and get infected within that 24-48 hour window of taking it

yeah I know everyone says "saturates your tissues" but that's useless if it's not in your bloodstream to go where the covid is, ivermectin doesn't spontaneously leave your tissues to go find covid like some kind of antibody responding to signaling

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[-] Haitchpeasauce | 2 points | Oct 30 2020 01:45:44

I think once per week is sufficient for a moderate risk case because they are not being exposed to the virus daily, it's all about risk. Within a 1 week period, if they were infected, they are then in incubation which can be 3-5 days before symptoms. There would be enough drug in the serum and lung tissues to be protective until the next dose.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 01:45:41

ivermectin doesn't spontaneously leave your tissues to go find covid like some kind of antibody responding to signaling

But it may leak into the blood stream. Did you ever see the graph of the blood levels of cattle given ivermectin via the Medincell injection? It was supposed to be good for three months; observed blood levels dropped, then after 3 months, more like 6, they started rising again?!

the once a week 12mg as prophylaxis just seems completely implausible unless you get really lucky with timing and get infected within that 24-48 hour window of taking it

Agree. That's why I take it twice a week. ;)

You're smart, know a lot of stuff that I don't. This seems oxymoronic -- but aside from an actual covid-19 test, is there anything to indicate infection before becoming symptomatic?

I really really wish I could buy a bunch of rapid antigen tests. They've been available in some parts of Latin America for a couple months. Take them daily. When I'm infected, take a BIG dose of ivermectin.

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[-] Haitchpeasauce | 3 points | Oct 30 2020 02:00:55

We actually don't want Ivermectin in the blood, we want it in the type 2 pneumocytes of the lung and the ciliated epithelial cells of the nasopharynx.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 02:02:41

So administration by emulsifier. OK.

The world seems to be having a lot of success with ivermectin in the blood -- but I take your point that it could be targeted better.

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[-] Haitchpeasauce | 2 points | Oct 30 2020 02:07:05

IVM is lipophilic so it reaches the tissues via the blood stream. I may have missed the point in this thread.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 02:17:36

I was following you until now.

We actually don't want Ivermectin in the blood

I guess you meant that we need the ivermectin to move through the blood stream to the relevant tissues.

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[-] Haitchpeasauce | 2 points | Oct 30 2020 02:19:25

That's what I mean :)

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[-] thaw4188 | 2 points | Oct 30 2020 02:07:05

those tests are only like 70% accurate and cost $30 a pop so that's not really economic - they are working on that $1 litmus strip test but that's not coming for months if ever

it's a subjective measurement but loss of smell is almost a guarantee of infection, but it doesn't happen to everyone (it didn't happen to me until after the first week of innate immune response with fever, so that was useless)

some people only get GI-like infection and never get respiratory

but even before I got a fever my heartrate just shot up like mad and wouldn't come down, my body knew something was up and was stressing out, I went to bed and then woke up with fever much later

look don't panic, we have SO much more knowledge and tools now compared to even over the summer, definitely more since March

if you get fever, even if it turns out to be the flu it still safe to then take the ivermectin, just won't likely help flu, if it's covid and you catch it early, probably sick two weeks and it will never get to pneunomia, etc. which is what all the nightmares are about

I can't remember but I think you are under 50 which also is far more in your favor compared to me

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[-] TrumpLyftAlles | 2 points | Oct 30 2020 02:16:06

Good answer, thanks.

those tests are only like 70% accurate

If you drink Michael Mina's koolaid, they're lower sensitivity is good because they register positive at peak viral load -- which would be a good time to take a lot of ivermectin. They not inaccurate, per se; they're less sensitive than PCR.

/r/Covid19Testing

(Does that link work for you?)

I can't remember but I think you are under 50

Unfortunately no: I was born during the Truman Administration. When I was a kid, the Dead Sea was just sick. (Wow, that's a really old joke I haven't pulled out in years.)

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[-] thaw4188 | 2 points | Oct 30 2020 02:39:49

btw another important detail to how sick I got is that I had the flu back in February, so even by May my system was probably still not back to 100%, it was a "perfect storm"

what's interesting is because the flu was still in my recent memory I got to compare it to covid and wow was covid so much worse - I was able to keep running daily though the flu (much slower) but with covid there was no way that was happening

so I still think as long as you take ivermectin at first sign of fever, etc. you will fair far better than I ever did

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 06:17:39

What a terrible double-whammy. I take it you've gotten a flu shot recently?

I still think as long as you take ivermectin at first sign of fever, etc. you will fair far better than I ever did

I hope (1) I don't catch the virus ever, (2) I don't catch it before I get the vaccine, (3) the vaccine works for me, and/or (4) a BIG dose of ivermectin handles it, if I ever DO catch the virus.

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[-] thaw4188 | 2 points | Oct 30 2020 15:43:56

I refuse to step into any building anymore (since May) until everyone has a covid vax so I can't get a flu shot in a store, it's been quite a dilemma.

But my doctor, who is amazing and the luckiest thing in my entire unlucky life, has said he is willing to send his nurse out to the parking lot and give me the shot while I sit in my car with window half-down. Yeah he's that considerate, all my life, a real gift to medical world when you hear of other horror stories.

I'm just waiting as long as I can to make sure I am recovered as much as possible, even the flu shot has risks and mild side-effects, I am thinking the week before thanksgiving before cases explode since everyone insists on gatherings despite clear evidence it's moronic.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 22:20:45

I refuse to step into any building anymore (since May) until everyone has a covid vax so I can't get a flu shot in a store, it's been quite a dilemma.

Wow, you're even more paranoid than me! Totally understandable after your ordeal.

But my doctor, who is amazing and the luckiest thing in my entire unlucky life, has said he is willing to send his nurse out to the parking lot and give me the shot while I sit in my car with window half-down.

A prince among doctors! Really, that's outstanding.

I'm just waiting as long as I can to make sure I am recovered as much as possible, even the flu shot has risks and mild side-effects, I am thinking the week before thanksgiving before cases explode since everyone insists on gatherings despite clear evidence it's moronic.

You could catch flu tomorrow. IMO you shouldn't wait.

As ever and always, good luck to you. I hope you make a full recovery.

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[-] thaw4188 | 2 points | Oct 30 2020 23:32:04

I don't want to scare people because I don't think this will happen to others anymore with all we know about the virus and treatment finally but once you spend a week heaving your chest as hard as you can while already on an oxygen machine to just barely maintain an spO2 of 80%, you will learn new levels of paranoia and fear if you survive

I couldn't handle it again, it was like drowning, for days

I barely had any grey hair before, now lots and it's falling out, that's how stressful, never want to go through that again

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 23:47:21

<<shudder

I barely had any grey hair before, now lots and it's falling out, that's how stressful, never want to go through that again

It's cool that just the gray is falling out!

(sorry, lame joke)

once you spend a week heaving your chest as hard as you can while already on an oxygen machine to just barely maintain an spO2 of 80%, you will learn new levels of paranoia and fear if you survive

I get it, why you're scared of entering buildings. You went through the wringer.

But you made it through!

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[-] Haitchpeasauce | 2 points | Oct 30 2020 01:51:42

I currently consider Ivermectin as a broad antiviral with strong targeting of RNA virus activity. The next question is how long this molecule is active within the cell?

Prophylaxis should be targeted similar to the Zagazig and Aguirre studies, given to high risk contacts rather than to whole populations. Move proactively, targeted and swiftly, and we will beat this pandemic.

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[-] TrumpLyftAlles | 1 points | Oct 30 2020 01:56:22

high risk contacts

I'm high-risk 6 or 7 ways, depending on whether blood type A is still considered a risk factor. ;)

rather than to whole populations

Not that anyone is proposing that outside of some specific locales of Latin America and India -- but what's your objection? Safety? Unproven efficacy?

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[-] Haitchpeasauce | 2 points | Oct 30 2020 02:05:09

That is, if you are in a high infection area or in contact with known cases. In Australia we have very few cases, so it makes little sense to drug the whole population.

What is my objection? Higher chance of encountering an adverse event, higher concentrations of IVM in the waterways is probably a bad idea, higher pressure for viruses escaping the MOA of Ivermectin. Basically don't use a drug more than you need to.

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[-] TrumpLyftAlles | 2 points | Oct 30 2020 02:06:39

Higher chance of encountering an adverse event, higher concentrations of IVM in the waterways is probably a bad idea, higher pressure for viruses escaping the MOA of Ivermectin. Basically don't use a drug more than you need to.

All good reasons. I'm selfish about covid19, putting myself before those considerations.

Apparently dung beetles are being adversely affected by treating large animals (horses, cows, pigs) with ivermectin.

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[-] stereomatch | 3 points | Oct 30 2020 12:33:45

Wow - compared to Oct 22, 2020 version of MATH+ protocol PDF which was mentioned here:

https://www.reddit.com/r/ivermectin/comments/jhclo7/_/ MATH+ protocol lists ivermectin as highly recommended for early covid19 (day1-8 viral replication stage) - (2020-10-22)

This current Oct 29, 2020 version now lists Ivermectin EVEN for severe hospitalized patients!!

And now highlights Ivermectin in RED highlights at ALL stages - from prophylaxis to mild to severe hospitalized.

The timeline graph in the MATH+ protocol PDF now has Ivermectin listed as useful for all stages.

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[-] massimaux | 1 points | Oct 30 2020 15:02:48

This is great, but it's extremely important that Dr. Marik becomes a "superspreader" of this protocol.

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[-] thaw4188 | 2 points | Oct 29 2020 23:50:54

that document has turned into some serious quality over this past year

initially was not so impressed, now it is well researched/referenced

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[-] Ok-Film-9049 | 3 points | Oct 30 2020 07:36:49

Really in testing to hear your experience and conclusions. I have resisted weekly dosing but have a substantial supply of IVM. In Manchester in UK and so many friends have been testing positive in last 2 weeks. Have enrolled on Novavax vaccine trial for next Tuesday. Will find out if have antibodies but this will mean I got off very easily because no clear symptoms. My plan is to make moderate dose if in contact with someone infected. Big dose if symptomatic. Feeling guilty that I am not able to get friends on board about IVM. It takes a lot of effort to get someone from no knowledge, to take some horse paste. I have tried a couple of times but it is as if you are suggesting colloidal silver.

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[-] thaw4188 | 1 points | Oct 30 2020 15:47:59

I suspect if the trial for the vax knows you are on IVM they will reject you and it's wrong if you don't tell them as it will mess up the result data. Something ethical to consider.

The IVM will prevent you from having covid for long so the vax antibodies might not take hold. Also a possibility the vax antibodies the IVM do not get along, you might be one of the first test cases hopefully with not bad results.

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[-] Ok-Film-9049 | 1 points | Oct 30 2020 16:39:46

Thanks for the input. Haven't taken IVM yet. Tricky dilemma but wouldn't take IVM unless have clear symptoms

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[-] RodRWA | 2 points | Oct 31 2020 22:46:21

Here's a direct link to Dr. Paul Marik's video. Re promoting IVERMECTIN, this has to be the most important video that I've seen to date. It makes a mockery of the elitists who insist that only Clinical Trial results count, while being so arrogant, dogmatic & lacking in empathy that they disregard all the lives that IVERMECTIN could have been saving while they fiddle around with their "double blinds" & "placebos". "Grrrr" to quote u/TrumpLyftAlles, our marvellous & active moderator! These elitists even rate a mention from the good doctor when he says: ".... they should come down from their ivory towers." Well said Doc, & many, many congratulations on producing an excellent video which very well may save the World! You probably deserve a Nobel prize.

IVERMECTIN: Save the planet from Covid-19

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