msa57injnb7epls4nbuj | 1 points | Oct 29 2020 08:17:15

Difference in ivermectin intended for humans vs animals? (Sorry x-post, I didn’t get an answer there)

/r/medical/comments/jidqwh/difference_in_ivermectin_intended_for_humans_vs/

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[-] TrumpLyftAlles | 2 points | Oct 29 2020 10:37:13

IMO: Same drug, different additional inactive ingredients.

From this post:

Thanks for the excellent question! It made me look up the Material Safety Data Sheet for the horse paste.

The other ingredients are pigment (< 5%), thickening agents (15%), and vehicle solvent (bal) (?). None of those have a classification as toxic or not. Ivermectin is "Toxic" in the ingredients list.

From here:

Ivermectin is a white to yellowish-white, nonhygroscopic, crystalline powder with a melting point of about 155°C. It is insoluble in water but is freely soluble in methanol and soluble in 95% ethanol. STROMECTOL is available in 3-mg tablets containing the following inactive ingredients: microcrystalline cellulose, pregelatinized starch, magnesium stearate, butylated hydroxyanisole, and citric acid powder (anhydrous).

You might be interested in this post that has links to about 20 Amazon reviews by people who consumed the horse paste.

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[-] thaw4188 | 1 points | Oct 29 2020 13:15:01

btw there's no such thing as a prophylactic dose

that's literally never been proven because it only has an 18 hour half life

not only is 10mg too little unless you are under 100 pounds, it's out of your system a day later

as far as animal safety, human pill manufacturing has ZERO supervision in the USA and produced elsewhere like India, the FDA has inspected factories in India like once or never, it's all self-reporting

so imaging what's going on with animal pills where there's even less liability than zero

it comes down to profit, what corners can they cut for more profit, I don't think there's many other than sanitary conditions

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[-] TrumpLyftAlles | 1 points | Oct 29 2020 17:49:58

btw there's no such thing as a prophylactic dose

Do you mean the prophylactic dose is not known? In the IVERCAR 788 study, IIRC they took 12mg once a week. That's the trial where they did carrageenan nasal spray too, but one of the researchers said that in another protocol that left out the carrageenan, the results were similar.

so imaging what's going on with animal pills where there's even less liability than zero

(Ordinary) horses cost around $3000 to buy and a similar number annually to maintain. There's over 9 million horses in the US. To sell to that market, makers want to provide a quality product. If Durvet or another manufacturer of horse paste produced a bad batch, I think there would be lots of law suits.

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[-] rraak | 1 points | Oct 29 2020 13:45:19

It's less ideal but it's unlikely to permanently cause harm. It has the active ingredient but may have different binders and fillers, so I would prefer to take it instead of doing nothing at all.

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[-] IcyEven | 1 points | Oct 29 2020 16:49:18

Currently, I use the 1% bovine injectable. I already had that on hand as I use it with livestock and also cut it to use as heartworm preventative, always orally.1% makes it easy for me to figure doses. I have also taken a dose

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[-] TrumpLyftAlles | 1 points | Oct 29 2020 17:41:06

Hi, Icy, can you please help me out? I bought a bottle of "AGRI-MECTIN injection for Cattle and Swine, 1% Sterile Solution" with the idea of using it with a nebulizer. Is that like your bovine injectable? How do you take it? With a syringe? How many ML do you take, for what weight?

The bottle has the guidance...

Recommended dose:

Cattle: 1 ML per 110 pounds
Swine: 1 ML per 75 pounds

For subcutaneous use only. Use automatic syringe only.

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[-] IcyEven | 1 points | Oct 29 2020 19:07:35

TrumpLyftAlles , yes the 1% injectable is the same. Ivomec is made by Merial, the bottle says made in Brazil. There are lots of other manufacturers. Key is always work with the 1% and it is easy to figure doses. There is a table here: COVID-19: POST-EXPOSURE PROPHYLAXIS WITH IVERMECTIN IN CONTACTS. At Homes, Places of Work, Nursing Homes, Prisons, and Others,posted last week. Sorry- my first reddit post and not very savvy,lol.It is divided into pills and 1% solution, based on kg.

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[-] IcyEven | 1 points | Oct 29 2020 19:09:28

I took it mixed in ginger ale after a meal.

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[-] msa57injnb7epls4nbuj | 1 points | Oct 29 2020 19:12:17

is ivomec for humans?

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[-] msa57injnb7epls4nbuj | 1 points | Oct 29 2020 19:14:07

How about ivermectin tablets made by Beijing Agrichina? apparently it's for sheep and pigs. would you take it?

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[-] IcyEven | 1 points | Oct 29 2020 22:54:31

Ivomec is veterinary ivermectin. I don’t have any information on veterinary ivermectin tablets so can’t comment on that.

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[-] Then_Flamingo | 1 points | Apr 03 2021 17:52:58

I got parasites as big as my arm ..........

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