TrumpLyftAlles | 5 points
Miscellaneous comments about prophylaxis with ivermectin from the "Ivermectin MD Team" Facebook group (World 2020-07 - 2020-09)The Facebook group has a lot of doctors who are using ivermectin to treat covid-19 patients. Dr. Aguirre is pretty prominent there. It's a private group, meaning you have to be admitted. I urge any MDs or health professionals to join.
The main thing I learned from this exercise is that there's no consensus on the prophylactic dose or frequency that ivermectin should be taken -- which makes sense, given that there is so little research published thus far about dosing and prophylaxis (actually, none AFAIK). I personally find Dr. Aguirre credible, because he is on the front-line treating patients and has a bent toward research. The fact remains that we just don't know how much taken how often provides protection against catching covid-19.
Paragraph breaks indicate that it's a different post. Sometimes there are threads, which I did not represent well in the notes. Maybe I'll try again one of these days.
You could use redditsearch.io to search this sub for "prophylaxis" and create a report about what's been posted to the sub -- with links to the various articles, etc!! This is the search (though you could look for "prophylactic" too; that might find additional comments). Let me know if you want to undertake this.
The comments from Facebook:
Dr. Aguirre After the 1st Dose, the 2nd Dose is taken in 7 days and then repeated every 14 days (every 2 weeks). In the case of doctors and people who are exposed to places with a high viral load (hospitals, markets, or the like), it would be repeated every 7 days, and this also includes their contacts who are men over 50 and women over 70. old. Contacts are the people with whom you cohabit at home, also those interned in a nursing home, in case you are a health person who comes to this place.
Sharing the protocols from Indian State of Uttar Pradesh For prophylaxis Tab. Ivermectin 12 mg (200microgram/kg) On Day 1, Day 7 & Day 30 2 hrs after dinner. Followed by every 30 days 1 tab of 12mg till pandemic is over. To be taken by all high risk people & frontline health workers. For +ve asymptomatic & with mild symptoms Tab Ivermectin 12 mg for 3 days along with Doxycycline (100) twice for 5 days.
what is the background of Adam Gaertner? MD? PhD? apparently he is an expert in virology but googling does not reveal his background. I only ask because I came across his assertion that long term use of ivermectin can cause autoimmune problems - what is this based on? If we have data that this works as prophylaxis many people will start taking it every 7-10days in high risk occupation (teacher included) but there does not seem to be much data on long term chronic prophylactic use. Anyone have any publication to share on this? Thanks
Good morning, please what is the prophylaxis suggestion for kids returning to school in USA? My daughters are 7 and 8 years old. My husband and myself just taking ivermectin every Sunday since August according to Dr Gustavo protocol ... 🙏 zero problem. Response: The recommendation by the two best ivermectin advocates doctors in brasil is 6mg ivermectin for every 30kg of body weight every 15 days for prophylaxis, for treatment is 6mg of ivermectin per every 30kg of body weight for 3 consecutive days
i've read of 12mg ivermectin per week for prophylaxis . sounds right. the Chinese found 12mg got people good in 5 days but some immediately relapsed so they went to 24 for sick people. makes 12mg per week reasonable for prophylaxis. I've noticed a lot of groups of people , like work , medical or not taking 12mg / 2 weeks with success , i'd be willing to try 3 weeks.
A NOTE ON COVID-19 PROPHYLAXIS Ivermectin is effective and safe for prophylaxis in the recommended dose (0.2 mg/kg). Personally, I prefer biweekly schedule to reduce the risk of overload (not that we have heard anything of overload yet, just to stay on a safe side). Addition of anything, that DOES NOT HURT (Vitamins C, D, Zinc, Calcium and such) can be used. Just note, that these substances should be part of a regular health scheme, not restricted exclusively for CoViD-19 prevention.
In my PERSONAL (and debatable) opinion, Doxycyclin, Azithromycin or any other antibiotic use should be restricted to infection treatment, not to be considered part of the prevention.
Here is why: An antibiotic course, when initated, should always be completed, meaning that the drug should be taken for at least 5 consecutive days. Otherwise it is considered semieffective underdosing, contributing to resistance development among the pathogenis bacterial strains.
If you chose IVM + Doxy protocol (with or without Zinc) Doxy should be taken for 5 days every two weeks (or almost continuously, when a weekly IVM is decided). Such shemes definitely are antibiotics overuse.
Please, think it over, how Doxy or Azithromycin are contributing. Allegedly, some antiviral activity, and mostly prevention of bacterial superinfection. May be, prevention of the cytokine storm. All justified, when the virus is actually present in the body. But what benefit, when there is no actual infection? NOTE: This is my PPERSONAL Opinion, open to debate and I invite any and all of you for discussion. I might have overlooked something, or unaware of existing facts. This note is a suggestion, not a recommendation. Think and act as you see fit. Thank you!
I would like to know about prophylaxis and therapeutic dosage in different countries. I bilieve in prophylaxis use and take Ivermectin each 15 days.
This is the treatment. But I use it as prophylaxis - negative serology or IgG + = single dose by weight, repeating every 6/6 months. For fellow health professionals, who are in the front line or ICU, in addition to this single dose, I recommend taking 1 tablet every day that you are in the hospital as a preventative.
Prophylatic use of ivermectin has two schools of thoughts. 1) the drug is eliminated very quickly from the body, so protection is for 24 hours.So next day you are unprotected. It is a good character of the drug that it is eliminated very fast. But it is useless in this regard. 2) use it once a week, and just treat any virus went inside your body. Since virus take one week or more to be active, this option will cure any assymptimaric infection or a developing infection. So, it is two sides. For a healthcare professional, it can be used as post exposure prophylaxis.
Prophylatic use of ivermectin has two schools of thoughts. 1) the drug is eliminated very quickly from the body, so protection is for 24 hours.So next day you are unprotected. It is a good character of the drug that it is eliminated very fast. But it is useless in this regard. 2) use it once a week, and just treat any virus went inside your body. Since virus take one week or more to be active, this option will cure any assymptimaric infection or a developing infection. So, it is two sides. For a healthcare professional, it can be used as post exposure prophylaxis.
what about dogs who use it once a month for heart worms? The protection lasts a month
You can't use Ivermectin everyday, as we don't know the toxicity in daily use.
6 mg of toxicity? Toxicity if used 3x 200 mcg / kg per day !!!
I have several colleagues who work in the ICU and take it every day !!!
Dr. Aguirre
DOSE PER KILO OF PRE-EXPOSURE PROPHYLAXIS WITH IvermectinE IN EXPOSED PERSONS Attached is the PDF document of the Pre-Exposure Prophylaxis Table. From the previously sent version I have added a column with the Dose for each weight in Kilos. If you are a person with low exposure, you can adjust the Doses to your particular situation, for example, take Ivermectin only when you are going to a place with a high viral load (markets, airports, land terminals, hospitals, etc.), and where there is a risk of transmission of the disease. In this case, the doses would not be given exactly every 2 weeks, but the person gives it on the days that they will have the greatest exposure. We must differentiate the Pre-Exposure Prophylaxis (which occurs periodically), from the Post-Exposure Prophylaxis (PPE) which is indicated to the Contacts and which is given on time when there has been contact with a confirmed case of COVID-19.
Dr. Aguirre's table shows doses at 200mcg/kg.
[-] TrumpLyftAlles | 1 points
I came across this Dr. Aguirre post, which offers concrete advice about prophylaxis.
Abstract Pre-exposure Prophylaxis (PrEP) consists of people at high risk of contracting COVID-19 taking medications periodically to prevent the virus from establishing in the mucosa and spreading through the body. When taken weekly or every 2 weeks, we are observing that it has a high effectiveness in preventing contracting COVID-19. PrEP becomes less effective when it is taken every 30 to 45 days. In people who have been using PrEP, we are seeing that Ivermectin reduces the risk of contracting the virus by approximately 99% when taken weekly, and by 94% if taken every 2 weeks (every 14 days). In people who are not exposed to places with high viral load, it could be justified to give doses every 14 days,
[-] TrumpLyftAlles | 1 points | Nov 07 2020 21:19:40
Sandor Toth
For health care staff I suggest 10 days prophylaxis protocol. Here in a neavily exposed unit staff have taken 2 weeks prevention protocol. 2 of 50 people got infected on 12th and 13th day of IVM taken. Both passed the infection with minimal symptoms. So 14 days seems to be not 100% adequate, while 10 days apparently enough.
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