New study. Still waiting for the formal report. Everything so far is vague. :(
High Dose, Rapid Virus Elimination
Adrián Lifchitz, professor of Pharmacology at Unicen, was the lead for the study of ivermectin concentrations in plasma samples of the trial subjects. “We found that the medication produced a rapid viral elimination from the body and this helps to reduce the probability of infection. The effect that ivermectin causes on the rate of disappearance of the virus depends on the amount of the drug that is absorbed (amount that enters the organism), after taking it orally. This becomes a proof of concept of high scientific value: it confirms the need to use dose levels higher than those traditionally applied,” according to the Conicet researcher and member of Civetan.
Another variable in dosing is how ivermectin taken - if the spec sheet for ivermectin says eating with fatty meal increases bioavailability by 2.5x - then how ivermectin taken should also be documented by studies else you will miss variability in dose essentially.
Just making a general comment - not specific to this study.
[-] TrumpLyftAlles | 3 points | Sep 27 2020 10:11:30
New study. Still waiting for the formal report. Everything so far is vague. :(
High Dose, Rapid Virus Elimination
Adrián Lifchitz, professor of Pharmacology at Unicen, was the lead for the study of ivermectin concentrations in plasma samples of the trial subjects. “We found that the medication produced a rapid viral elimination from the body and this helps to reduce the probability of infection. The effect that ivermectin causes on the rate of disappearance of the virus depends on the amount of the drug that is absorbed (amount that enters the organism), after taking it orally. This becomes a proof of concept of high scientific value: it confirms the need to use dose levels higher than those traditionally applied,” according to the Conicet researcher and member of Civetan.
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[-] stereomatch | 3 points | Sep 27 2020 12:29:59
Another variable in dosing is how ivermectin taken - if the spec sheet for ivermectin says eating with fatty meal increases bioavailability by 2.5x - then how ivermectin taken should also be documented by studies else you will miss variability in dose essentially.
Just making a general comment - not specific to this study.
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[-] TrumpLyftAlles | 2 points | Sep 27 2020 12:56:31
That's a good point! I vaguely recall that at least one study protocol specified taking IVM 2 hours after eating. Not sure about that.
The safety study that found 10 x 200mcg/kg safe said 2.6. ;)
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