Prophylaxis! (huge grin emoji)

TL;DR: 33 people confirmed to be covid-negative on day 3 were given 1 dose of ivermectin. None were infected during the 21 days following, based on a clinical inspection.

After reading the abstract:

Meh. Very small N, too brief an observation period, no PCR test at the end of the study period.

If I saw this in April, when the study was done, it would be huge. It's not, though, IMO --given the larger Egypt and Argentina prophylaxis trials.

Still, more evidence is more evidence.

SUMMARY
Prophylaxis is aimed at preventing the development of infection and disease after exposure to an infectious agent. The WHO, PAHO and other recognized organizations indicate Post-Exposure Prophylaxis (PEP) for cases of HIV, Hepatitis B, C and TB infection, and there are studies that report the use of Ivermectin as Prophylaxis in cases of Scabies. To date, studies of PPE in COVID-19 using Hydroxychloroquine have been reported, and there are at least 2 ongoing studies on Ivermectin Prophylaxis. In this document, the first 2 cases of prophylaxis with Ivermectin performed in health personnel on April 7, 2020 are reported and the development of a study of PPE with Ivermectin for COVID-19 is detailed.

MATERIAL AND METHODS
For the PPE study, the following Protocol was followed: In all persons who met the definition of being Contacts and who were negative in the laboratory test for SARS CoV-2, they were indicated a dose of Ivermectin of 0.2 mg per kilo of weight, for 1 day. Additionally, only in men over 45 years of age it was indicated to evaluate giving a second dose of Ivermectin on the second or third day, this would be done in case other people in the home or place of residence developed characteristic symptoms of COVID-19. The presence of COVID-19 symptoms within the first 3 days of taking Ivermectin was established as the Exclusion Criterion, this because the incubation period for COVID-19 is 5 days on average. Daily clinical follow-up was indicated until day 21 after taking Ivermectin.

Interesting innovation, excluding those who (apparently) were already infected.

RESULTS
Of a total of 40 people enrolled, 7 were positive to the laboratory test and were therefore excluded from the study, leaving 33 participants. In the clinical evaluations carried out within the first 3 days, no person with symptoms was identified, so no molecular testing was performed on any, nor was a second dose of ivermectin indicated, nor were participants excluded from the study. Daily clinical follow-up was continued for 21 days after taking Ivermectin, and none of the people manifested symptoms, that is, none developed the COVID-19 disease.

They looked for symptoms instead of doing a PCR test, at the end of the 21 days.

CONCLUSION
The result of the present study finds the utility of Ivermectin as Prophylaxis in COVID-19. Given the high morbidity and mortality caused by COVID-19, Prophylaxis should be taken into account as a complementary preventive measure to those already established, considering it necessary to carry out clinical studies on Prophylaxis in COVID-19 with a significant number of people.

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Someone able to explain why Ivermectin has no support on a major basis?

Why are countries with massive outbreaks out of control (India) not just trying this with massive numbers of people?

The scientific community needs to learn how to move with a faster response time during serious events where life is at stake

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Did they only get one dose and 21 days later still tested negative? Am I reading it right?

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2020-09-23: Dr. Aquirre has re-released his report, this time with improved English. Here.

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