Top-level task force finds anti-parasitic drug ivermectin ineffective against coronavirus (India, 2020-07-14)

[-] TrumpLyftAlles | 3 points | Jul 21 2020 17:45:19

A brief, negative result for ivermectin.

I couldn't grab the text. Anyone a member?

This decision clearly isn't definitive, given the subsequent (2020-07-20) webinar about ivermectin.

[-] strongerthrulife | 3 points | Jul 21 2020 20:29:44

There’s Zero randomized blind controlled studies completed, that’s what this is saying.

It doesn’t mean it doesn’t work

Studies are on going, garbage article

[-] thaw4188 | 2 points | Jul 21 2020 19:04:51

lol there is no way it's not effective

they need to show extended proof

based on the text it looks like they didn't actually test anything themselves and just hand-waived it away

[-] lemallette | 2 points | Jul 22 2020 01:33:22

Absence of evidence is NOT evidence of absence.

[-] nojox | 1 points | Jul 23 2020 21:26:19

The other story posted here shows a video interview which states it prominently being used: https://np.reddit.com/r/ivermectin/comments/hwn0pb/exercised_amp_kept_fit_yet_i_tested_positive_for/

So they won't formally include it until they have proof, i.e., until there are a couple of studies with results.

I think it's the same case with bromhexine (Tabriz Iran study and China study)

[-] thaw4188 | 2 points | Jul 21 2020 19:14:01

text hidden here:

https://webcache.googleusercontent.com/search?q=cache:https://m.economictimes.com/industry/healthcare/biotech/pharmaceuticals/anti-parasitic-drug-is-not-that-useful-against-covid-no-decision-on-biocons-itolizumab-yet/articleshow/77010290.cms

NEW DELHI: A top-level task force on Covid-19 has found inconclusive evidence to approve antiparasitic drug ivermectin for Covid management. In a meeting held on July 14 to review the evidence, the task force headed by Niti Aayog member VK Paul decided against recommending the drug in the clinical management protocol.

While the panel was also supposed to take a decision on the use of Biocon's itolizumab, the matter could not be taken up. Experts say current evidence does not suggest that ivermectin is useful against Covid-19. “There is no conclusive proof to use the drug in clinical management. We cannot recommend the drug for management of Covid based on a little evidence,” said Naveet Wig, the head of the department of medicine at All India Institute of Medical Sciences. Wig is a member of the task force. He said: “If the clinicians are using it in their wisdom, they can do it but every drug cannot be recommended in the national guidelines.”

Widely prescribed in India and parts of South America to treat infections from worms, ivermectin has been used since the 1980s in creams and lotions for head lice.In a meeting held on July 14 to review the evidence, the task force headed by Niti Aayog member VK Paul decided against recommending the drug in the clinical management protocol. While the panel was also supposed to take a decision on the use of Biocon's itolizumab, the matter could not be taken up.Experts say current evidence does not suggest that ivermectin is useful against Covid-19. “There is no conclusive proof to use the drug in clinical management. We cannot recommend the drug for management of Covid based on a little evidence,” said Naveet Wig, the head of the Department of Medicine at All India Institute of Medical Sciences. Wig is a member of the task force. He said: “If the clinicians are using it in their wisdom, they can do it but every drug cannot be recommended in the national guidelines.”Widely prescribed in India and parts of South America to treat infections from worms, ivermectin has been used since the 1980s in creams and lotions for head lice.

Earlier, the Indian Council of Medical Research (ICMR) had also begun reviewing a combination of ivermectin and antibiotic doxycycline which Bangladesh doctors claim is yielding full recovery. Some Latin American countries are also betting on ivermectin. However, the ICMR doesn't recommend it. “The ICMR is continuously evaluating the treatment guidelines. The drugs which have proved to be efficacious should be added to the new protocol and hence a meeting is convened time to time,” a person in the know said, speaking on the condition of anonymity.In its earlier updated protocol, the ICMR recommended the use of dexamethasone as an alternative to methylprednisolone for managing moderate to severe cases of Covid-19.Wig has advised against prescribing these high-end drugs. “Majority of patients can be managed by oxygenation, corticosteroids, antivirals and management of comorbidities. These drugs are not simple and can cause immune suppression. Though some can be given these drugs on a case-to-case basis, but these cannot be included in the national protocol without any strong evidence,” he said.

[-] nakedrickjames | 2 points | Jul 21 2020 19:32:22

Seems like the headline is misleading, not so much as they found it was *ineffective*, just no conclusive evidence that it *was* effective, so far. Similar to the CDC's stance, currently. Still need to see data from those higher powered randomized, controlled trials, esp. with zinc (of which ivermectin is an ionophore).

[-] Qoti | 1 points | Jul 21 2020 20:35:04

Yep, they just kept the profesional stance that they can't recommend something nation wide until there is further evidence, they even said it is ok for clinicians to use it if they consider so. Title is super misleading.

[-] shaunak_dey | 2 points | Jul 23 2020 19:38:48

super misleading title. possible paid journalism by big pharma companies?

[-] pezo1919 | 1 points | Jul 21 2020 18:32:43

how is that possible?!