Two firsts: A study in Lebanon, found via the Chinese trial registry site!
Title: In vivo use of ivermectin (IVR) for treatment for corona virus infected patients: a randomized controlled trial
The objectives of the study are to test if
* Ivermectin is an effective treatment for COVID-19 infected patients;
* Ivermectin will reduce significantly viral load within 72 hours of its administration to COVID-19 infected patients.
Description:
I. First of all a pilot case control study will be conducted on asymptomatic adults positive for COVID-19.
a) The subjects will be contacted based on a list provided by different laboratories performing the PCR, the aim of study and its potential outcomes will be explained
b) The participants will be divided into two groups (cases and control) with respect to matching criteria (age, gender, past medical history, BMI .) and the viral load of each one will be documented.
c) A baseline laboratory testing for ALT, AST and creatinine will be done and documented
d) The cases will receive Ivermectin as per the below doses and the control will receive placebo (powder based tablets). 9mg PO once if 45kg - 64kg 12mg PO once; if 65kg-84kg 150mcg/kg if body weight ≥ 85 Kg
e) 72-hours after the intervention the participant will undergo PCR to precise their viral loads and the laboratory tests done as baseline will be repeated.
f) The patient will be provided with hotline number to inform the team about any adverse reaction or any symptom during the intervention period.
II. If promising results will be favor the use of Ivermectin, its application to moderate and severe case will be discussed with treating physicians as per protocol already prepared by the research team.
Summary:
N=30, randomized into an experimental group that will receive one dose of ivermectin (amount based on weight), and a control group that will receive placebo.
No completion date that I could find. I emailed the researcher asking about that.
[-] TrumpLyftAlles | 2 points | Jun 15 2020 19:27:02
Two firsts: A study in Lebanon, found via the Chinese trial registry site!
Title: In vivo use of ivermectin (IVR) for treatment for corona virus infected patients: a randomized controlled trial
The objectives of the study are to test if * Ivermectin is an effective treatment for COVID-19 infected patients;
* Ivermectin will reduce significantly viral load within 72 hours of its administration to COVID-19 infected patients.
Description:
I. First of all a pilot case control study will be conducted on asymptomatic adults positive for COVID-19.
a) The subjects will be contacted based on a list provided by different laboratories performing the PCR, the aim of study and its potential outcomes will be explained
b) The participants will be divided into two groups (cases and control) with respect to matching criteria (age, gender, past medical history, BMI .) and the viral load of each one will be documented.
c) A baseline laboratory testing for ALT, AST and creatinine will be done and documented
d) The cases will receive Ivermectin as per the below doses and the control will receive placebo (powder based tablets).
9mg PO once if 45kg - 64kg 12mg PO once;
if 65kg-84kg 150mcg/kg if body weight ≥ 85 Kg
e) 72-hours after the intervention the participant will undergo PCR to precise their viral loads and the laboratory tests done as baseline will be repeated.
f) The patient will be provided with hotline number to inform the team about any adverse reaction or any symptom during the intervention period.
II. If promising results will be favor the use of Ivermectin, its application to moderate and severe case will be discussed with treating physicians as per protocol already prepared by the research team.
Summary:
N=30, randomized into an experimental group that will receive one dose of ivermectin (amount based on weight), and a control group that will receive placebo.
No completion date that I could find. I emailed the researcher asking about that.
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