This is incredible: ivermectin is still working against a parasite three years after the treatment.
Lymphatic filariasis is a neglected tropical disease, caused by the nematode parasites Wuchereria bancrofti and brugia species, that is targeted for elimination by mass drug administration.1 In 2018, we published results from a clinical trial in Papua New Guinea that showed that a single dose of ivermectin plus diethylcarbamazine plus albendazole (three-drug regimen) cleared microfilaremia in 55 of 57 persons with bancroftian filariasis for 3 years after treatment. This result was far superior to that obtained with the previous standard regimen of diethylcarbamazine plus albendazole (two-drug regimen). Consequently, the World Health Organization modified its guidelines to recommend the three-drug regimen for filariasis elimination outside sub-Saharan Africa in regions that either had not started a mass drug administration or had delivered fewer than four annual rounds of diethylcarbamazine–albendazole and in regions that had not met thresholds for transmission interruption.3 Merck expanded its annual donation of ivermectin by 100 million additional doses to help facilitate this change, with 68 million people expected to receive treatment with the three-drug combination in 2020.
The success is attributable to ivermctin, even though it is one of three drugs in the treatment, because "single dose of ivermectin plus diethylcarbamazine plus albendazole" is "far superior to that obtained with the previous standard regimen of diethylcarbamazine plus albendazole".
Not covid-19 related, but yet another testimonial to the magical ability of ivermectin to have LONG term positive effects.
If in fact ivermectin turns out to be the magic pill for covid-19 -- dosing annually or even less often may provide protect from the virus.
[-] TrumpLyftAlles | 2 points | May 16 2020 01:19:19
This is incredible: ivermectin is still working against a parasite three years after the treatment.
Lymphatic filariasis is a neglected tropical disease, caused by the nematode parasites Wuchereria bancrofti and brugia species, that is targeted for elimination by mass drug administration.1 In 2018, we published results from a clinical trial in Papua New Guinea that showed that a single dose of ivermectin plus diethylcarbamazine plus albendazole (three-drug regimen) cleared microfilaremia in 55 of 57 persons with bancroftian filariasis for 3 years after treatment. This result was far superior to that obtained with the previous standard regimen of diethylcarbamazine plus albendazole (two-drug regimen). Consequently, the World Health Organization modified its guidelines to recommend the three-drug regimen for filariasis elimination outside sub-Saharan Africa in regions that either had not started a mass drug administration or had delivered fewer than four annual rounds of diethylcarbamazine–albendazole and in regions that had not met thresholds for transmission interruption.3 Merck expanded its annual donation of ivermectin by 100 million additional doses to help facilitate this change, with 68 million people expected to receive treatment with the three-drug combination in 2020.
The success is attributable to ivermctin, even though it is one of three drugs in the treatment, because "single dose of ivermectin plus diethylcarbamazine plus albendazole" is "far superior to that obtained with the previous standard regimen of diethylcarbamazine plus albendazole".
Not covid-19 related, but yet another testimonial to the magical ability of ivermectin to have LONG term positive effects.
If in fact ivermectin turns out to be the magic pill for covid-19 -- dosing annually or even less often may provide protect from the virus.
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